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Nitrate and Nitrite Metabolism in Aging Rats: A Comparative Study.

Barbora Piknova1, Ji Won Park1, Samantha M Thomas1

  • 1Molecular Medicine Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, MD 20892, USA.

Nutrients
|June 10, 2023
PubMed
Summary

Aging reduces nitric oxide (NO) availability. While nitrate levels increase and nitrite levels decrease in older rats, the nitrate reduction pathway remains functional, suggesting altered NO synthesis or signaling.

Keywords:
agingnitratenitric oxidenitrite

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