Factors Associated with Intestinal Polyp Recurrence after Electroresection.

Area of Science:

• Gastroenterology
• Endoscopic Surgery
• Oncology

Background:

• Intestinal polyps are common, and high-frequency electroresection is a standard endoscopic treatment.
• Understanding recurrence patterns and associated risk factors is crucial for effective patient management and surveillance strategies.

Purpose of the Study:

• To determine the recurrence rate of intestinal polyps following colonoscopic high-frequency electroresection.
• To identify and analyze risk factors associated with polyp recurrence after this endoscopic procedure.

Main Methods:

• An observational study analyzed data from 240 patients undergoing high-frequency electroresection for intestinal polyps.
• Patients were followed for two years to assess polyp recurrence.
• Unconditional binary logistic regression was used to identify significant risk factors for recurrence.

Main Results:

• Factors significantly associated with higher recurrence rates included older age (≥60 years), multiple polyps (≥3), larger polyp diameter (≥2 cm), adenomatous histology, and Helicobacter pylori infection.
• Metabolic syndrome and elevated C-reactive protein levels were also more prevalent in the recurrence group.
• Multivariate analysis confirmed age, polyp number, polyp diameter, adenomatous type, and metabolic syndrome as independent predictors of recurrence.

Conclusions:

• Age, polyp burden (number and size), adenomatous histology, and metabolic syndrome are key factors predicting intestinal polyp recurrence after endoscopic resection.
• These findings can inform personalized follow-up protocols to improve patient outcomes and reduce the risk of recurrent polyps.