Related Experiment Video
Updated: Jul 27, 2025

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Depression Is Associated With Non-Home Discharge After Coronary Artery Bypass Graft
Ryan M Holcomb1, Ahsan Zil-E-Ali2, Robert Gonzalez3
1Department of Surgery, Pennsylvania State University College of Medicine, Hershey, Pennsylvania.
Depression significantly increases the risk of non-home discharge after coronary artery bypass graft (CABG) surgery. This finding highlights the need for better preoperative screening of depression in cardiac patients.
Area of Science:
- Cardiology
- Psychiatry
- Health Services Research
Background:
- Depression is prevalent in patients with coronary artery disease (CAD).
- Depression is linked to adverse outcomes after cardiac procedures.
- Non-home discharge (NHD) is a critical quality metric following major surgery.
Purpose of the Study:
- To investigate the association between depression and NHD after coronary artery bypass graft (CABG) surgery.
- To determine if depression independently predicts NHD in CABG patients.
Main Methods:
- Analysis of the 2018 National Inpatient Sample database for CABG cases.
- Utilized ICD-10 codes to identify patients with and without depression.
- Employed multivariable logistic regression to control for confounders and assess the association between depression and NHD, and prolonged length of stay (LOS).
Main Results:
- 8.8% of 31,309 CABG patients had a history of depression.
- Depressed patients had significantly higher rates of NHD (70% increased odds) and prolonged LOS (24% increased odds) after adjustment.
- Depressed patients were younger, more often female, from lower income quartiles, and had greater medical complexity.
Conclusions:
- A history of depression is independently associated with a higher likelihood of non-home discharge following CABG.
- This study is the first to demonstrate this association in a national sample.
- Improved preoperative identification of depression is crucial for risk stratification and optimizing discharge planning for CABG patients.
Related Concept Videos
Coronary Artery Disease V: Interprofessional Care
Acute Coronary Syndrome IV: Interprofessional Care
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Peripheral Artery Disease V: Postoperative Nursing Management
Coronary Artery Disease III: Clinical Manifestations
Depressive Disorders: MDD and Dysthymia

