Related Experiment Video
Updated: Jul 26, 2025

12:08
Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
18.9K
One Size Fits All Versus Individualized Medicine in Type 1 Diabetes Management
1Midwest Pediatric Specialists, P.A., Overland Park, Kansas, USA.
Diabetes Technology & Therapeutics
|June 12, 2023
Summary
Diabetes management requires daily self-care, but adherence varies due to individual factors. This review explores personalized diabetes care using technology for proactive management and prevention.
Area of Science:
- Endocrinology
- Metabolic Diseases
- Personalized Medicine
Background:
- Diabetes mellitus is a chronic condition demanding significant daily self-management from patients.
- Current treatment approaches often adopt a "one size fits all" model, which can be insufficient due to individual patient variability in physical, emotional, and lifestyle factors impacting adherence.
- Limited treatment options historically necessitated standardized care protocols.
Approach:
- This article reviews the historical evolution of diabetes care, highlighting key milestones.
- It establishes the rationale for transitioning towards individualized diabetes management strategies.
- A roadmap is proposed for leveraging current and emerging technologies to facilitate this shift.
Key Points:
- Patient adherence to diabetes treatment is influenced by a complex interplay of personal physical abilities, emotional well-being, and lifestyle circumstances.
- The limitations of standardized care models underscore the need for personalized therapeutic approaches.
- Technological advancements offer opportunities to tailor diabetes management to individual patient needs.
Conclusions:
- Individualized care is essential for optimizing diabetes management and improving patient outcomes.
- The integration of technology is pivotal for moving from reactive treatment to proactive disease management and prevention.
- Future diabetes care paradigms should embrace personalization to address the diverse needs of patients effectively.
Related Concept Videos
Diabetes: Management and Pharmacotherapy
319
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
319
Insulin: Dosing Regimen and Adverse Effects
215
Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
215
Diabetes Mellitus: Overview and Type I Subtype
2.8K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.8K
Diabetes Mellitus: Type 2 and Gestational
2.6K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.6K
Insulin Formulations: Types and Delivery
237
Insulin preparations are categorized by their duration of action into short-acting and long-acting types. Two strategies are used to modify insulin's absorption and pharmacokinetic profile: slowing the absorption post-subcutaneous injection, or altering human insulin's amino acid sequence or protein structure. These changes retain the insulin's ability to bind to the insulin receptor, but alter its behavior in solution or after injection.
Short-acting insulins are divided into...
Short-acting insulins are divided into...
237
Carbohydrate Metabolism
11.3K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.3K

