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A method for calculating left ventricular ejection fraction noninvasively from left ventricular arterial coupling
Yukiko Yamazaki1, Yuka Matsuki2, Kenji Shigemi3
1Intensive Care Medicine, University of Fukui Hospital, Fukui, Japan.
BMC Anesthesiology
|June 12, 2023
Summary
This study introduces a novel non-invasive method to estimate ejection fraction (EF) using left ventricular arterial coupling. This approach offers a potential alternative for continuous cardiac function monitoring, overcoming limitations of current ultrasonography techniques.
Area of Science:
- Cardiology
- Biomedical Engineering
- Physiology
Background:
- Ejection fraction (EF) is crucial for cardiac function assessment but current ultrasonography methods lack continuous, non-invasive monitoring capabilities.
- Continuous EF assessment is vital for clinical cardiology and anesthesia management.
Purpose of the Study:
- To develop a non-invasive method for estimating EF using the left ventricular arterial coupling ratio (Ees/Ea).
- To approximate EF by calculating left ventricular efficiency (Eff) using a novel formula based on Ees/Ea.
Main Methods:
- Ees/Ea was non-invasively estimated using parameters from the VeSera 1000/1500 vascular screening system.
- Left ventricular efficiency (Eff) was calculated using a new formula involving Ees/Ea to approximate EF (EFeff).
- EFeff was compared with EF measured via transthoracic echocardiography (EFecho) in 44 healthy adults.
Main Results:
- A positive correlation (R²=0.219, p<0.05) was observed between EFecho and EFeff.
- Bland-Altman analysis showed limits of agreement of -7.5% to 24.4% with a percentage error of 24%.
Conclusions:
- Non-invasive EF estimation using left ventricular arterial coupling is feasible.
- This method may provide a new avenue for continuous cardiac function monitoring.
