Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Stroke Volume01:27

Regulation of Stroke Volume

3.3K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interleukins and Psoriasis.

Journal of cutaneous medicine and surgery·2024
Same author

The gut microbiome: an important role in neurodegenerative diseases and their therapeutic advances.

Molecular and cellular biochemistry·2023
Same author

Establishing and evaluating physician-pharmacist collaborative clinics to manage patients with type 2 diabetes in primary hospitals in Hunan province: study protocol of a multi-site randomized controlled trial in the era of COVID-19 pandemic.

BMC health services research·2022
Same author

Molecular phylogenetic and morphometric analysis of population structure and demography of endangered threadfin fish Eleutheronema from Indo-Pacific waters.

Scientific reports·2022
Same author

Exploration of the total-body PET/CT reconstruction protocol with ultra-low <sup>18</sup>F-FDG activity over a wide range of patient body mass indices.

EJNMMI physics·2022
Same author

Co-delivery of EGCG and lycopene <i>via</i> a pickering double emulsion induced synergistic hypolipidemic effect.

Food & function·2022
Same journal

EEG Functional Connectivity Associated With Antidepressant Response to Transcutaneous Electrical Cranial-Auricular Acupoint Stimulation.

CNS neuroscience & therapeutics·2026
Same journal

Cingulate Gradient Dysfunction in End-Stage Renal Disease: Associations With Clinical Phenotypes and Exploratory Transcriptomic Signatures.

CNS neuroscience & therapeutics·2026
Same journal

Dual Antiplatelet Therapy in Acute Branch Atheromatous Disease (BAD)-Related Stroke: A Multicenter Propensity-Matched Cohort Analysis.

CNS neuroscience & therapeutics·2026
Same journal

Postherpetic Neuralgia: Mechanisms, Risk Factors, and Stratified Management-A Narrative Review.

CNS neuroscience & therapeutics·2026
Same journal

FAST BEE (Keeping FAST First): A Public Stroke Education Design to Drive EMS Activation.

CNS neuroscience & therapeutics·2026
Same journal

Conventional MRI-Based Semantic Features for Differentiation of Pediatric Medulloblastoma and Ependymoma in the Fourth Ventricle: Insights From a Multi-Center Retrospective Study.

CNS neuroscience & therapeutics·2026
See all related articles

Related Experiment Video

Updated: Jul 26, 2025

Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research
07:34

Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research

Published on: December 15, 2023

2.2K

The interaction between intestinal microenvironment and stroke.

Linna Zhao1,2,3, Jie Xiao1,2,4, Songlin Li1,2,4

  • 1First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.

CNS Neuroscience & Therapeutics
|June 13, 2023
PubMed
Summary
This summary is machine-generated.

Altering the gut environment may offer new stroke treatments. Targeting the intestinal microenvironment, including gut microbiota, shows promise for improving outcomes in stroke survivors and reducing disability.

Keywords:
gut microbiotaintestinal immunityintestinal microenvironmentneuroinflammationstroketreatment

More Related Videos

Investigating Alterations in Caecum Microbiota After Traumatic Brain Injury in Mice
04:29

Investigating Alterations in Caecum Microbiota After Traumatic Brain Injury in Mice

Published on: September 19, 2019

6.3K
Visualization of Neutrophil Extracellular Traps in Mesenteric Venules After Mesenteric Ischemia-Reperfusion Injury via Intravital Microscopy
07:05

Visualization of Neutrophil Extracellular Traps in Mesenteric Venules After Mesenteric Ischemia-Reperfusion Injury via Intravital Microscopy

Published on: September 27, 2024

517

Related Experiment Videos

Last Updated: Jul 26, 2025

Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research
07:34

Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research

Published on: December 15, 2023

2.2K
Investigating Alterations in Caecum Microbiota After Traumatic Brain Injury in Mice
04:29

Investigating Alterations in Caecum Microbiota After Traumatic Brain Injury in Mice

Published on: September 19, 2019

6.3K
Visualization of Neutrophil Extracellular Traps in Mesenteric Venules After Mesenteric Ischemia-Reperfusion Injury via Intravital Microscopy
07:05

Visualization of Neutrophil Extracellular Traps in Mesenteric Venules After Mesenteric Ischemia-Reperfusion Injury via Intravital Microscopy

Published on: September 27, 2024

517

Area of Science:

  • Neuroscience
  • Immunology
  • Gastroenterology

Background:

  • Stroke is a leading cause of death and disability, with limited treatment options for survivors.
  • Inflammation and immune responses are key features following a stroke.
  • The gastrointestinal tract plays a crucial role in immune function and communicates with the brain via the brain-gut axis.

Purpose of the Study:

  • To review the structure and function of the intestinal microenvironment.
  • To highlight the brain-gut axis's relationship with stroke.
  • To discuss therapeutic strategies targeting the intestinal environment for stroke treatment.

Main Methods:

  • Literature review of experimental and clinical studies.
  • Analysis of the bidirectional communication between the gut and the brain.
  • Exploration of the impact of the intestinal microenvironment on stroke outcomes.

Main Results:

  • The intestinal microenvironment significantly influences neurological function and cerebral ischemic outcomes.
  • The gut microbiota is a key component of the intestinal microenvironment.
  • Emerging research highlights the dynamic relationship between the gut and stroke.

Conclusions:

  • Modulating the intestinal microenvironment, particularly the gut microbiota, presents a novel therapeutic avenue for stroke.
  • Improving the gut environment may enhance recovery and reduce long-term disability in stroke patients.
  • Targeting the gut microbiota offers a promising strategy for future stroke treatment and management.