An Unusual Cause of Intractable Hiccups

Area of Science:

• Medical Case Reports
• Gastroenterology
• Thoracic Surgery

Background:

• Hiccups are typically transient, but intractable cases can significantly impact quality of life.
• Differential diagnosis for persistent hiccups is broad, ranging from central nervous system disorders to gastrointestinal issues.
• Mediastinal masses are uncommon causes of intractable hiccups.

Observation:

• A patient presented with prolonged, intractable hiccups.
• Diagnostic imaging revealed a mediastinal lipoma.
• The lipoma was identified as the causative agent for the persistent hiccups.

Findings:

• Mediastinal lipoma can present as a rare cause of intractable hiccups.
• Surgical or conservative management of the lipoma may resolve hiccups.
• Understanding the pathophysiology of hiccups is crucial for diagnosis and treatment.

Implications:

• This case highlights the importance of considering rare etiologies for refractory symptoms.
• Highlights the need for thorough investigation in cases of persistent hiccups.
• Suggests potential for novel treatment strategies targeting the underlying cause of hiccups.