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Related Concept Videos

Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

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Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
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Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

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Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
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Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

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DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
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Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

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Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
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Related Experiment Video

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Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
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[New solutions for an old problem : Current developments in oral contrast agents].

Thomas Fork1,2, Ingvar Adnerhill3,4, Olof Böök4

  • 1Emeritus aus der Abteilung Radiologie, Universitätsklinikum Lund, Malmö, Schweden. thomas.fork@lumentab.com.

Radiologie (Heidelberg, Germany)
|June 14, 2023
PubMed
Summary

A new CT technique using Lumentin® oral contrast agent provides detailed small bowel imaging comparable to MRI. This improves CT scan quality and reduces patient waiting times for diagnostic procedures.

Keywords:
Bowel loop delineationComputertomographyHounsfield unitsMagnetic resonance tomographyPeroral bowel contrast

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Area of Science:

  • Radiology
  • Medical Imaging
  • Gastroenterology

Context:

  • MRI is preferred for small intestine imaging due to superior detail.
  • Limited MRI availability leads to significant patient wait times.
  • There is a need for improved CT techniques for small bowel visualization.

Purpose:

  • To develop an improved CT technique mimicking MRI's T1-weighted sequences.
  • To create an oral contrast agent for CT that enhances the intestinal wall while maintaining a low-signal lumen.

Summary:

  • A novel, stable, foamy oral contrast agent (Lumentin®) with 44% air content was developed.
  • CT scans using Lumentin® demonstrated excellent distribution, lumen distension, and mucosal enhancement in volunteers and patients.
  • Diagnostic image quality was comparable or superior to MRI, with fewer and milder side effects than conventional agents.

Impact:

  • Lumentin® significantly enhances diagnostic CT image quality for small bowel imaging.
  • This innovation offers a viable alternative to MRI, potentially reducing wait times.
  • Promising preliminary results from experimental MRI studies suggest broader applications.