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Hyperbaric oxygen therapy for patients with fibromyalgia: a systematic review protocol
Xiaochai Han1, Yu He1, Xiangnan Yuan1
1Department of Rehabilitation, Shengjing Hospital of China Medical University, Shenyang, China.
BMJ Open
|June 14, 2023
Summary
This systematic review evaluates hyperbaric oxygen therapy (HBOT) for fibromyalgia (FM). It aims to determine if HBOT effectively reduces pain and improves quality of life for FM patients.
Area of Science:
- Medical research
- Clinical trials
- Systematic review
Background:
- Fibromyalgia (FM) is a widespread chronic condition causing pain, fatigue, and cognitive issues.
- FM significantly impacts individuals and society, necessitating effective treatment options.
- Hyperbaric oxygen therapy (HBOT) shows potential for alleviating FM symptoms.
Purpose of the Study:
- To systematically assess the effectiveness and safety of HBOT for fibromyalgia.
- To provide evidence for the clinical implementation of HBOT in FM management.
- To support decision-making processes for fibromyalgia treatment programs.
Main Methods:
- Systematic review and meta-analysis protocol adhering to PRISMA guidelines.
- Comprehensive search of ten major databases for randomized controlled trials (RCTs) in English or Chinese.
- Independent screening, data extraction, and risk of bias assessment using the PEDro Scale by two reviewers.
Main Results:
- The study will synthesize findings from identified RCTs on HBOT for FM.
- Both narrative and quantitative syntheses will be performed.
- A meta-analysis will be conducted using Review Manager V.5.3 software.
Conclusions:
- The review will provide a comprehensive assessment of HBOT's efficacy and safety in FM.
- Findings will inform clinical practice and treatment guidelines for fibromyalgia.
- Dissemination of results will occur through a peer-reviewed journal publication.

