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Updated: Jul 26, 2025

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Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
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Fertility preservation options for transgender and nonbinary individuals
Jensen Reckhow1, Hakan Kula2, Samir Babayev3
1Obstetrics & Gynecology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55907, USA.
Therapeutic Advances in Endocrinology and Metabolism
|June 16, 2023
Summary
Fertility preservation counseling is crucial for transgender and nonbinary individuals undergoing gender-affirming care. Improving access to these services requires a multidisciplinary approach and further research for optimal patient outcomes.
Area of Science:
- Reproductive medicine
- Gender-affirming healthcare
Background:
- Transgender and nonbinary individuals face significant barriers in accessing healthcare.
- Gender-affirming therapies (hormone therapy, surgery) can impact future fertility.
- Existing fertility preservation services are often inadequate for this population.
Purpose of the Study:
- To highlight the critical need for improved fertility preservation counseling and services for transgender and nonbinary individuals.
- To underscore the complexity of fertility preservation in this demographic.
- To identify areas for future research and improved care frameworks.
Main Methods:
- Review of current challenges in fertility preservation for transgender and nonbinary patients.
- Analysis of factors influencing fertility preservation method selection (pubertal status, therapy type).
- Discussion of the necessity for a multidisciplinary approach.
Main Results:
- Fertility preservation options are contingent on individual patient factors and treatment pathways.
- Current service delivery models are often insufficient, requiring enhancement.
- A comprehensive, integrated care framework is lacking.
Conclusions:
- Enhanced fertility preservation counseling and services are essential for transgender and nonbinary individuals.
- Further research is needed to identify stakeholders and optimal care delivery models.
- Optimizing fertility preservation offers significant opportunities to improve care for this underserved population.
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