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Molecular docking analysis of melamine with nuclear factor erythroid 2-related factor 2 and succinate dehydrogenase
Nitish Rai1, Sheemona Chowdhary2, Deepak Kumar2
1Department of Biotechnology, Mohanlal Sukhadia University, Udaipur, Rajasthan, India.
Abstract:
Melamine consumption causes oxidative stress by an unknown mechanism. Therefore, it is of interest to analyze the interaction of melamine with two important proteins involved in oxidative stress biology namely, nuclear factor erythroid 2-related factor 2 and succinate dehydrogenase. The molecular docking data shows the melamine binding with these two proteins at critical residues. These interactions can be logically perceived for the causation of melamine induced oxidative stress.
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