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Analyzing Synaptic Modulation of Drosophila melanogaster Photoreceptors after Exposure to Prolonged Light
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A closer look at the synapse: dlg1[4K] enables cell-specific visualization of PSD-95/DLG1
Emily L Hendricks1, Faith L W Liebl1
1Department of Biological Sciences, Southern Illinois University Edwardsville, Edwardsville, IL 62025, USA.
Abstract:
The PSD-95 homolog, DLG1, is important for excitatory synapse structure and function throughout the Drosophila nervous system. In this issue of Cell Reports Methods, Parisi et al. present a tool, dlg1[4K], that enables cell-specific DLG1 visualization without altering basal synaptic physiology. This tool will potentially enhance our understanding of neuronal development and function in both circuits and individual synapses.
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