Related Experiment Video
Updated: Jul 26, 2025
DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments
Published on: January 27, 2016
[DNA Fragment Enrichment for High-Throughput Sequencing]
A N Sinyakov1,2, E V Kostina1
1Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090 Russia.
New DNA synthesizers create oligonucleotides for enriching genomic fragments. Methods like molecular hybridization, PCR, and CRISPR-Cas9 are used for research and diagnostics.
Area of Science:
- Molecular Biology
- Genomics
- Biotechnology
Background:
- Next-generation DNA synthesizers, particularly microarray-based systems, are crucial for producing custom oligonucleotides.
- Oligonucleotides play a vital role in various molecular biology techniques.
- Target genomic fragment enrichment is essential for accurate downstream analysis.
Conclusions:
- Oligonucleotides from advanced synthesizers are effective tools for genomic fragment enrichment.
- The discussed methods offer powerful approaches for molecular research and diagnostics.
- These advancements facilitate precise and efficient analysis of target DNA sequences.
More Related Videos
12:23In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses
Published on: September 7, 2022
08:15gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
Published on: October 6, 2014
Related Concept Videos
03:21RNA-seq
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
01:24DNA Isolation