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Updated: Jul 26, 2025

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Published on: February 26, 2021
Therapeutic Advances in Eosinophilic Granulomatosis with Polyangiitis
Jessica L Bloom1, Carol A Langford2, Michael E Wechsler3
1Section of Rheumatology, Department of Pediatrics, University of Colorado School of Medicine, 13123 East 16th Avenue B-311, Aurora, CO 80045, USA.
Abstract:
Eosinophilic granulomatosis with polyangiitis (EGPA) is an eosinophilic vasculitis that affects a variety of organ systems. Historically, glucocorticoids and a variety of other immunosuppressants were used to abrogate the inflammation and tissue injury associated with EGPA. The management of EGPA has evolved greatly during the last decade with the development of novel targeted therapeutics that have resulted in significantly improved outcomes for these patients, with many more novel targeted therapies emerging.
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