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Assessing Therapeutic Angiogenesis in a Murine Model of Hindlimb Ischemia
Published on: June 8, 2019
Techniques Providing Endpoints for Revascularization in Chronic Limb-Threatening Ischemia
Oleksandra Kutsenko1, Jill Sommerset2, Venita Chandra3
1Department of Radiology, Miami Cardiac and Vascular Institute, Miami, Florida.
Abstract:
It is frequently difficult to estimate the revascularization endpoint in patients with chronic limb-threatening ischemia where there may be extensive multifocal multiarterial disease. There have been attempts to identify an endpoint for revascularization procedures, but none has become the standard of care. An ideal indicator of an endpoint can objectively quantify tissue perfusion, predict wound healing, and is easily and efficiently used intraprocedurally to assist real-time decision making on whether adequate perfusion has been reached. Candidate techniques to evaluate endpoints post-revascularization are discussed here.
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