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Updated: Jul 26, 2025

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
Published on: June 7, 2015
Technical note: Feasibility of gating for dynamic trajectory radiotherapy - Mechanical accuracy and dosimetric
Hannes A Loebner1, Daniel Frauchiger1, Silvan Mueller1
1Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.
Respiratory gating successfully improved dosimetric accuracy during dynamic trajectory radiotherapy (DTRT) delivery, a novel technique extending volumetric modulated arc therapy (VMAT). Mechanical accuracy remained consistent with and without gating, demonstrating feasibility for advanced cancer treatment.
Area of Science:
- Medical Physics
- Radiation Oncology
- Radiotherapy Technology
Background:
- Dynamic trajectory radiotherapy (DTRT) enhances volumetric modulated arc therapy (VMAT) with simultaneous table and collimator rotations during beam delivery.
- The impact of intrafraction motion on DTRT, particularly the interplay between patient and machine motion, remains largely unexplored.
Purpose of the Study:
- To experimentally evaluate the technical feasibility of respiratory gating during DTRT delivery.
- To quantify the mechanical and dosimetric accuracy of gated DTRT.
Main Methods:
- A DTRT and VMAT plan for lung cancer was delivered to a motion phantom on a TrueBeam system.
- Respiratory gating was triggered using an external marker, and mechanical accuracy was analyzed from logfiles.
- Dosimetric accuracy was assessed using gamma evaluation (3% global/2 mm).
Main Results:
- DTRT and VMAT plans were successfully delivered with and without gating across various motion traces.
- Mechanical accuracy deviations were minimal (<0.14° for gantry, <0.08 mm for MLC).
- Gating significantly improved dosimetric performance, with gamma passing rates ≥96.7% (gated) compared to ≤88.3% (ungated).
Conclusions:
- Respiratory gating was successfully implemented during DTRT delivery on a TrueBeam system for the first time.
- Mechanical accuracy was comparable between VMAT and DTRT, with and without gating.
- Gating substantially enhanced the dosimetric accuracy of both DTRT and VMAT, indicating its clinical potential.
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