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Factors Affecting Dissolution: Particle Size and Effective Surface Area01:23

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Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
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Correction: Lipid nanoparticle-based formulations for high-performance dentistry applications.

Isha Mutreja1, Dhiraj Kumar2, Ajeet Kaushik3

  • 1Minnesota Dental Research Center for Biomaterials and Biomechanics, Department of Restorative Sciences, University of Minnesota, Moos Health Science Tower, 515 Delaware Street S.E., Minneapolis, MN 55455, USA. imutreja@umn.edu.

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|June 21, 2023
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Summary

This correction clarifies details in a previous study on lipid nanoparticle formulations for advanced dental applications. It ensures accuracy for readers interested in biomaterials for dentistry.

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Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Dental Materials

Context:

  • Lipid nanoparticles (LNPs) are increasingly explored for advanced applications.
  • High-performance formulations are crucial for effective delivery in dentistry.
  • Previous research highlighted the potential of LNPs in dental applications.

Purpose:

  • To correct and clarify specific details within the original publication.
  • To ensure the scientific accuracy of the presented lipid nanoparticle formulations.
  • To provide an accurate reference for future research in dental biomaterials.

Summary:

  • The correction addresses specific points within the original article concerning lipid nanoparticle formulations.
  • It refines the description of formulation parameters and performance metrics.
  • Ensures the data and conclusions presented are precise and reproducible.

Impact:

  • Enhances the reliability of the original study for the scientific community.
  • Facilitates accurate understanding and application of LNP technology in dentistry.
  • Supports the development of next-generation dental biomaterials and therapies.