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Two-Dimensional (2D) materials in the detection of SARS-CoV-2
Aytekin Uzunoglu1, Evrim Gunes Altuntas2, Hasan Huseyin Ipekci1
1Faculty of Engineering, Metallurgical & Materials Engineering, Necmettin Erbakan University, Konya 42090, Turkey.
Summary
This review explores advanced biosensor technologies using 2D materials for rapid, accurate, and cost-effective SARS-CoV-2 detection, addressing limitations of current PCR-based methods.
Area of Science:
- Nanomaterials Science
- Biotechnology
- Analytical Chemistry
Background:
- The COVID-19 pandemic caused significant global health and economic challenges.
- Current SARS-CoV-2 detection methods, like PCR, have drawbacks including high cost, time consumption, and susceptibility to errors.
- There is a need for faster, more accessible, and reliable diagnostic tools.
Purpose of the Study:
- To critically review advancements in biosensor technologies for SARS-CoV-2 detection.
- To highlight the role of two-dimensional (2D) materials in developing novel sensors.
- To discuss current trends and future directions in 2D material-based SARS-CoV-2 sensing.
Main Methods:
- Review of scientific literature on 2D materials and biosensors for SARS-CoV-2 detection.
- Analysis of the properties of graphene, MXenes, and TMDs for sensor applications.
- Discussion of electrochemical (bio)sensor development using 2D materials.
Main Results:
- 2D materials offer unique properties for high-performance electrochemical biosensors.
- Biosensors based on 2D materials demonstrate potential for rapid, specific, and precise SARS-CoV-2 detection.
- These sensors present a promising low-cost alternative to traditional diagnostic methods.
Conclusions:
- 2D materials are pivotal in advancing SARS-CoV-2 detection technologies.
- Biosensor technologies utilizing 2D materials offer significant advantages over existing methods.
- Further development in this area is crucial for improved pandemic response and public health surveillance.
