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Updated: Jul 26, 2025

Determination of the Photoisomerization Quantum Yield of a Hydrazone Photoswitch
Published on: February 7, 2022
Highly Efficient Oxindole-Based Molecular Photoswitches
Daniel Doellerer1, Daisy R S Pooler1, Ainoa Guinart1
1Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.
Abstract:
3-Benzylidene-indoline-2-ones play a prominent role in the pharmaceutical industry due to the diverse biomedical applications of oxindole heterocycles. Despite the extensive reports on their biological properties, these compounds have hardly been studied for their photochemical activity. Here, we present 3-benzylidene-indoline-2-ones as a promising class of photoswitches with high yields, robust photochemical switching with quantum yields reaching up to 50 % and potential for biological applications.
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