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Updated: Jul 31, 2026

Human Internal Mammary Artery IMA Transplantation and Stenting: A Human Model to Study the Development of In-Stent Restenosis
Published on: May 9, 2012
Is the COMPASS pointing towards clinical equipoise for the right internal mammary artery?
1Department of Cardiac Surgery, Rabindranath Tagore International Institute of Cardiac Sciences, Narayana Health, 124, EM Bypass, Mukundapur, Kolkata, 700099 India.
Insights
The right internal mammary artery (RIMA) shows a high failure rate, challenging its use in coronary artery bypass grafting (CABG). Further research is needed to evaluate RIMA
Area of Science:
- Cardiovascular Surgery
- Vascular Grafting
Background:
- The right internal mammary artery (RIMA) is often considered a secondary graft choice in coronary artery bypass grafting (CABG).
- Recent cardiovascular guidelines recommend RIMA use with a Class IIa indication.
Purpose of the Study:
- To critically evaluate the efficacy and long-term patency of the RIMA as a coronary artery bypass graft conduit.
Main Methods:
- Analysis of data from the COMPASS-CABG sub-study.
- Assessment of graft failure rates associated with RIMA use.
Main Results:
- The COMPASS-CABG sub-study revealed a significantly high graft failure rate for the RIMA.
- This finding contrasts with previous recommendations for RIMA utilization.
Conclusions:
- The high failure rate observed necessitates a re-evaluation of the RIMA's role in CABG.
- Further scientific investigation and clinical studies are required to determine the optimal use of RIMA as a conduit.
Abstract:
The right internal mammary artery (RIMA) has been considered the second-best graft after the left internal mammary artery by many. Recent guidelines have awarded class IIa recommendation for using the RIMA. The findings of the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS)-coronary artery bypass grafting (CABG) sub-study showed a high graft failure rate for the RIMA. The findings of the study should initiate further scientific scrutiny of the RIMA and studies need to be carried out for further evaluation of the RIMA as a conduit.
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