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Paraesthesiae in multiple sclerosis.

E A Sanders, R J Arts

    Journal of the Neurological Sciences
    |July 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Paraesthesia is common in multiple sclerosis (MS), affecting 84% of patients. Abnormal somatosensory evoked responses (SSER) significantly correlate with impaired vibration, touch, and pain senses in MS patients.

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    Area of Science:

    • Neurology
    • Neuroscience
    • Clinical Medicine

    Background:

    • Paraesthesiae are a common neurological symptom.
    • Multiple sclerosis (MS) is a chronic autoimmune disease affecting the central nervous system.
    • Understanding the clinical features of paraesthesiae in MS is crucial for diagnosis and management.

    Purpose of the Study:

    • To analyze the clinical features of paraesthesiae in patients with multiple sclerosis (MS).
    • To investigate the association between paraesthesiae, sensory loss, and somatosensory evoked responses (SSER) in MS.

    Main Methods:

    • Analysis of clinical data from 127 patients with clinically definite multiple sclerosis (MS).
    • Assessment of paraesthesiae as a presenting symptom and their persistence.
    • Correlation of paraesthesiae with sensory loss and abnormal somatosensory evoked responses (SSER).

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    Main Results:

    • Paraesthesiae were a presenting symptom in 40% and persistent in 84% of MS patients.
    • Paraesthesiae were frequently associated with sensory loss, but this was not statistically significant.
    • Abnormal SSER showed statistically significant associations with diminished sense of vibration, touch, and pain.

    Conclusions:

    • Paraesthesiae are a highly prevalent symptom in multiple sclerosis.
    • While associated with sensory loss, the link between paraesthesiae and SSER requires further investigation.
    • Abnormal SSER strongly indicates sensory deficits in MS, particularly affecting vibration, touch, and pain perception.