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An essential overview of orofacial clefting
Serena V Martin1, Marc C Swan2
1Cleft Fellow, Spires Cleft Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 9DU, United Kingdom.
British Dental Journal
|June 22, 2023
Summary
Understanding facial embryology is key to orofacial clefting. This review covers epidemiology, classification, anatomy, and UK cleft care, highlighting future research potential.
Area of Science:
- Craniofacial embryology and developmental biology.
- Clinical anatomy and surgical reconstruction.
- Epidemiology and public health.
Background:
- Orofacial clefts are complex congenital conditions with significant phenotypic variation.
- Understanding embryologic development of the face is crucial for comprehending cleft anatomy.
- Current classification systems facilitate international research and audit.
Conclusions:
- A comprehensive understanding of facial embryology is essential for managing orofacial clefts.
- Standardized classification and robust auditing are critical for improving patient outcomes.
- Ongoing research, such as the Cleft Collective study, holds promise for elucidating causes and optimizing treatment.
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