Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Modified-Release Drug Delivery Systems: Stimuli-Activated01:30

Modified-Release Drug Delivery Systems: Stimuli-Activated

Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also called...
Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cigarette butt recycling in South Korea: environmental policy failure and the limits of extended producer responsibility.

Tobacco control·2026
Same author

EpCAM<sup>+</sup> Extracellular Vesicle PD-L1 Dynamics as a Predictive Biomarker of Immune Checkpoint Blockade Response.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

BRAF Mutation and Tumor Growth Kinetics during Active Surveillance of Papillary Thyroid Microcarcinoma: A Single-Center Retrospective Study.

Endocrinology and metabolism (Seoul, Korea)·2026
Same author

Charge-engineered cellulose nanofibril binders for PFAS-free, high-loading lithium battery positive electrodes.

Nature communications·2026
Same author

Association between the use of e-cigarettes and heated tobacco products and asthma prevalence in adolescents: A secondary dataset analysis of the Korea Youth Risk Behavior Survey 2022-2024.

Tobacco induced diseases·2026
Same author

The differential effects of stigma on mental health service use by age groups: A comparison study based on Korean nationwide survey 2011 and 2021.

Psychiatry research·2026

Related Experiment Video

Updated: Jun 14, 2026

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
05:11

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue

Published on: January 11, 2020

7.5K

A dual stimuli-responsive smart soft carrier using multi-material 4D printing.

Inyoung Choi1, Saeeun Jang2, Seunggyeom Jung1

  • 1School of Undergraduate Studies, Daegu Gyeongbuk Institute of Science & Technology (DGIST), Daegu 42988, South Korea. shpark12@dgist.ac.kr.

Materials Horizons
|June 23, 2023
PubMed
Summary

This study introduces a 4D printed smart soft carrier that uses dual stimuli for controlled cargo delivery. This adaptable carrier can safely transport delicate items and organisms using near-infrared light and magnetic fields.

More Related Videos

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization
07:28

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization

Published on: February 18, 2022

3.8K
Four-Dimensional Printing of Stimuli-Responsive Hydrogel-Based Soft Robots
05:43

Four-Dimensional Printing of Stimuli-Responsive Hydrogel-Based Soft Robots

Published on: January 13, 2023

3.0K

Related Experiment Videos

Last Updated: Jun 14, 2026

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
05:11

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue

Published on: January 11, 2020

7.5K
3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization
07:28

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization

Published on: February 18, 2022

3.8K
Four-Dimensional Printing of Stimuli-Responsive Hydrogel-Based Soft Robots
05:43

Four-Dimensional Printing of Stimuli-Responsive Hydrogel-Based Soft Robots

Published on: January 13, 2023

3.0K

Area of Science:

  • Materials Science
  • Biomedical Engineering
  • Robotics

Background:

  • Advanced materials enable novel functionalities in soft robotics.
  • Stimuli-responsive hydrogels are crucial for developing smart delivery systems.
  • 4D printing offers precise control over material shape and function over time.

Purpose of the Study:

  • To develop a 4D printed smart soft carrier for controlled cargo delivery.
  • To investigate the dual stimuli-responsive behavior (NIR and magnetic fields) of the carrier.
  • To demonstrate the carrier's capability in transporting various cargo, including delicate organisms.

Main Methods:

  • Fabrication of a hemispherical soft carrier using 4D printing with smart hydrogels.
  • Integration of thermo-responsive poly(N-isopropylacrylamide) (PNIPAM) and polyethylene glycol (PEG) hydrogels.
  • Incorporation of superparamagnetic iron oxide nanoparticles (SPIONs) for magnetic actuation and near-infrared (NIR) responsiveness.

Main Results:

  • The soft carrier demonstrated controlled opening and closing of its lid via temperature changes induced by NIR irradiation.
  • The carrier exhibited magnetic-driven movement in water using an external magnetic field.
  • Successful cargo delivery experiments were conducted with various cargo types and small marine organisms, showing no leakage or damage.

Conclusions:

  • The 4D printed smart soft carrier offers a versatile and adaptable platform for cargo and organism delivery.
  • Dual stimuli-responsive actuation (NIR and magnetic fields) allows for precise control over carrier function.
  • The technology holds promise for applications requiring safe and controlled transport of sensitive materials.