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Bladder Capacity in Women With Overactive Bladder Syndrome: A Cross-sectional Study
Luis López-Fando Lavalle1, Paola Calleja Hermosa2, Clara Velasco Balanza3
1Hospital La Princesa, Madrid, Spain.
Urology
|June 23, 2023
Summary
Bladder capacity measures in women with overactive bladder (OAB) are often reduced and do not correlate well between different assessment methods like cystomanometry and bladder diaries. This highlights challenges in evaluating OAB accurately.
Area of Science:
- Urology
- Gynecology
- Clinical Research
Background:
- Idiopathic overactive bladder syndrome (OAB) significantly impacts women's quality of life.
- Accurate assessment of bladder capacity is crucial for managing OAB symptoms.
Purpose of the Study:
- To evaluate bladder capacity in women with idiopathic OAB using bladder diaries, cystomanometry, and uroflowmetry.
- To assess the concordance between different measures of bladder capacity.
- To explore the relationship between bladder capacity and urinary frequency in OAB patients.
Main Methods:
- Observational, cross-sectional, multicentric study including female patients diagnosed with idiopathic OAB.
- Participants completed a 3-day bladder diary (3dBD) and underwent urodynamic studies.
- Bladder capacity was measured using maximum cystometric capacity (MCC), voided volume (VV) during uroflowmetry, and maximum (VVmax) and average (VVmed) voided volumes from the 3dBD.
Main Results:
- Bladder capacity measures, except VVmax, were diminished in OAB patients.
- Poor correlation was observed between different bladder capacity variables (ICC and weighted Kappa index <0.4).
- A weak negative linear relationship was found between 24-hour frequency and average VV (Pearson coefficient -0.344).
Conclusions:
- Maximum cystometric capacity (MCC) and average voided volume (VV) are reduced in OAB patients.
- MCC shows poor correlation with functional bladder volumes assessed by voiding diaries in the OAB population.
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