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Different hydration methods for the prevention of contrast-induced nephropathy in patients with elective percutaneous

Fei Chen1, Jingchao Lu1, Xiuchun Yang1

  • 1Department of Cardiology, the Second Hospital of Hebei Medical University and the Institute of Cardiocerebrovascular Disease of Hebei Province, Shijiazhuang, 050000, China.

BMC Cardiovascular Disorders
|June 24, 2023
PubMed

Insights

Postprocedure hydration is as effective as preprocedure hydration for preventing contrast-induced nephropathy (CIN) in patients undergoing percutaneous coronary intervention (PCI). This finding supports similar safety and efficacy for both hydration strategies in cardiac procedures.

Area of Science:

  • Cardiology
  • Nephrology
  • Radiology

Background:

  • Contrast-induced nephropathy (CIN) is a significant concern following cardiac procedures.
  • Hydration is the primary method for CIN prevention.
  • The optimal timing of hydration (pre- vs. postprocedure) remains debated.

Purpose of the Study:

  • To compare the effectiveness of preprocedure versus postprocedure hydration in preventing CIN.
  • To evaluate CIN incidence and adverse events in patients undergoing elective percutaneous coronary intervention (PCI).

Main Methods:

  • Retrospective study with propensity score matching.
  • Comparison of 198 postprocedure hydration cases with 396 preprocedure hydration cases.
  • Analysis of CIN incidence at 48 hours and major adverse events within 30 days post-PCI.

Main Results:

  • CIN incidence was 3.54% in the postprocedure group and 4.8% in the preprocedure group (p = 0.478), showing no significant difference.
  • Major adverse events were similar between groups (3.03% vs. 2.02%, p = 0.830).
  • Independent risk factors for CIN included diabetes, baseline BNP and cystatin C, and contrast agent dosage.

Conclusions:

  • Postprocedure hydration is an effective alternative to preprocedure hydration for CIN prevention in elective PCI.
  • Both hydration strategies demonstrate comparable efficacy and safety profiles.
Abstract

Keywords:
Contrast-induced nephropathyCoronary heart diseaseHydrationPercutaneous coronary intervention

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