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Reply to the Letter to the Editor «Frailty Is a Risk Factor for Falls in the Older Adults: A Systematic Review and Meta-Analysis».

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Related Experiment Video

Updated: Jul 25, 2025

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
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Frailty Is a Risk Factor for Falls in the Older Adults: A Systematic Review and Meta-Analysis.

Z-C Yang1, H Lin, G-H Jiang

  • 1Zhi-hao Wang, No.107, Wenhua West Road, Jinan, Shandong, 250012, China, Tel 0531-82166761,

The Journal of Nutrition, Health & Aging
|June 25, 2023
PubMed
Summary

Frailty significantly increases fall risk in older adults. The risk varies by assessment tool, with the FRAIL scale showing the highest association. Factors like gender and economic development also influence fall risk.

Keywords:
Elder peoplefallsfrailty

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Area of Science:

  • Gerontology and Geriatric Medicine
  • Public Health and Epidemiology
  • Clinical Medicine

Background:

  • Limited literature exists on the relationship between frailty and falls in older adults.
  • Understanding this association is crucial for developing targeted interventions to prevent falls in this vulnerable population.

Approach:

  • Systematic review and meta-analysis of 29 cohort studies, including over 1 million participants aged 65+.
  • Searched multiple English and Chinese databases from 2001 to October 2022.
  • Utilized Newcastle-Ottawa Scale for bias assessment and Stata/MP 17.0 for meta-analysis, including subgroup analyses.

Key Points:

  • Frailty is significantly associated with a higher risk of falls in older adults (RR=1.48).
  • The FRAIL scale demonstrated the highest fall risk association (RR=1.82).
  • Men exhibited a higher fall risk than women (RR=1.94).
  • Fall risk was highest in Oceania (RR=2.35) and developed countries (RR=1.44), with increased risk observed between 2013-2019.

Conclusions:

  • Frailty is a significant risk factor for falls in older adults, with risk varying by assessment tool and demographic factors.
  • The FRAIL scale, gender, geographical area, and economic development level are key factors influencing fall risk.
  • Selecting appropriate frailty assessment tools is essential for accurate identification and effective fall prevention strategies.