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Updated: Jul 25, 2025

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Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
Published on: October 11, 2018
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BenchMetrics Prob: benchmarking of probabilistic error/loss performance evaluation instruments for binary
1Pointr, Ankara, Turkey.
Summary
This study evaluates probabilistic performance metrics for binary classification, finding Mean Absolute Error (MAE) most robust for general use and Root Mean Squared Error (RMSE) best when large errors matter most. Avoid less reliable metrics like LogLoss and MAPE.
Area of Science:
- Machine Learning
- Statistical Modeling
- Computer Science
Background:
- Probabilistic error/loss metrics, common in regression, are increasingly used for binary classification.
- Existing methods lack systematic evaluation for their suitability in classification tasks.
Purpose of the Study:
- To systematically assess probabilistic instruments for binary classification performance evaluation.
- To identify weaknesses of current metrics and determine the most robust options.
Main Methods:
- A two-stage benchmarking method, BenchMetrics Prob, was developed.
- The method utilized five criteria and fourteen simulation cases with synthetic datasets.
- 31 instrument/instrument variants were tested.
Main Results:
- Mean Absolute Error (MAE) and Root Mean Squared Error (RMSE) were identified as the most robust metrics.
- MAE is recommended for general purposes due to its interpretability and [0, 1] range.
- RMSE is preferred when emphasizing larger errors.
Conclusions:
- Researchers should carefully select robust probabilistic metrics for binary classification performance evaluation.
- Metrics like LogLoss, MAPE, sMAPE, and MRAE demonstrated lower robustness and should be avoided.
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