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Diffuse pulmonary meningotheliomatosis

Anthony Nadrous1, Sushilkumar Sonavane2, Andras Khoor3

  • 1Division of Pulmonary, Allergy, and Sleep Medicine Mayo Clinic Florida Jacksonville Florida USA.

Respirology Case Reports
|June 26, 2023
PubMed

Insights

Diffuse pulmonary meningotheliomatosis (DPM) is a rare lung condition with tiny nodules. While often asymptomatic, DPM may be linked to lung cancers like adenocarcinoma.

Area of Science:

  • Pulmonary Medicine
  • Oncology
  • Radiology

Background:

  • Diffuse pulmonary meningotheliomatosis (DPM) is an exceedingly rare pulmonary disease.
  • It is characterized by numerous small, bilateral nodules resembling meningothelial cells.
  • A distinctive 'cheerio-sign' may be observed on medical imaging.

Purpose of the Study:

  • To summarize the key characteristics of Diffuse Pulmonary Meningotheliomatosis.
  • To highlight the typical clinical presentation and imaging findings.
  • To discuss the potential association with pulmonary malignancies.

Main Methods:

  • Literature review of existing case studies and research on DPM.
  • Analysis of imaging characteristics, including the 'cheerio-sign'.
  • Review of reported patient outcomes and associated conditions.

Main Results:

  • Most patients with DPM are asymptomatic.
  • The condition typically shows no significant disease progression.
  • A notable association exists between DPM and pulmonary malignancies, particularly lung adenocarcinoma.

Conclusions:

  • Diffuse pulmonary meningotheliomatosis is a rare condition with characteristic imaging findings.
  • It is generally benign in terms of progression and symptoms.
  • The potential link with lung adenocarcinoma warrants further investigation and awareness.
Keywords:
chest computed tomographypulmonary meningotheliomatosispulmonary nodule

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