Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Beaded fluorescence pattern of FTA-ABS test associated with malignancy.

S C Duncan, H O Perry, A L Schroeter

    Archives of Dermatology
    |March 1, 1979
    PubMed
    Summary

    A beaded immunofluorescence pattern in FTA-ABS tests can indicate false positives in SLE patients. This study also links this finding to colon cancer, suggesting a broader diagnostic relevance.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    An Analysis of the Relationship Between Parent and Adolescent Marijuana Use Via Generalized Estimating Equation Methodology.

    Multivariate behavioral research·2016
    Same author

    Approaches to Testing Interaction Effects Using Structural Equation Modeling Methodology.

    Multivariate behavioral research·2016
    Same author

    Latent Variable Modeling of Longitudinal and Multilevel Substance Use Data.

    Multivariate behavioral research·2016
    Same author

    Modeling Incomplete Longitudinal Substance Use Data Using Latent Variable Growth Curve Methodology.

    Multivariate behavioral research·2016
    Same author

    Natural course of cannabis use disorders.

    Psychological medicine·2014
    Same author

    Parent substance use as a predictor of adolescent use: A six-year lagged analysis.

    Annals of behavioral medicine : a publication of the Society of Behavioral Medicine·2013

    Area of Science:

    • Immunology
    • Medical Diagnostics
    • Oncology

    Background:

    • The FTA-ABS test is a standard diagnostic tool for syphilis.
    • A beaded immunofluorescence pattern is an uncommon finding during FTA-ABS testing.
    • This pattern has been previously associated with Systemic Lupus Erythematosus (SLE).

    Observation:

    • A beaded immunofluorescence pattern was observed during routine FTA-ABS testing.
    • This specific immunofluorescence finding was noted in a patient with carcinoma of the colon.

    Findings:

    • The beaded immunofluorescence pattern in FTA-ABS testing is strongly correlated with false-positive results in patients diagnosed with Systemic Lupus Erythematosus (SLE).
    • This report documents the occurrence of the beaded immunofluorescence pattern in a patient with colon cancer, suggesting a potential association beyond SLE.

    Implications:

    • The beaded immunofluorescence pattern may serve as an indicator for conditions beyond SLE, including certain malignancies.
    • Further research is warranted to explore the diagnostic utility of this immunofluorescence finding in oncology.
    • This observation could lead to revised interpretations of FTA-ABS test results in specific clinical contexts.

    Related Experiment Videos