APPLICATION OF PROBIOTIC ANTISEPSIS FOR PURULENT COMPLICATIONS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS.
Oleksandr Yu Ioffe1, Oleksandr P Stetsenko1, Stepan L Kindzer1
1BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.
Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|June 26, 2023
Summary
Probiotic antiseptics significantly accelerated wound healing in type 2 diabetes patients with purulent-necrotic wounds, reducing inflammatory markers and promoting tissue regeneration compared to traditional treatments.
Area of Science:
- Wound healing research
- Diabetology
- Microbiology
Background:
- Purulent-necrotic wounds are a serious complication in type 2 diabetes patients.
- Effective treatment strategies are crucial for improving patient outcomes.
Purpose of the Study:
- To evaluate the efficacy of probiotic antiseptics in treating purulent-necrotic wounds in type 2 diabetes patients.
- To compare the outcomes with traditional antiseptic treatments.
Main Methods:
- A study involving 66 patients with type 2 diabetes and purulent-necrotic wounds.
- Comparison of probiotic antiseptics (experimental group) versus traditional antiseptics (control group).
- Monitoring of pro-inflammatory markers (IL-6, TNF-a, CRP) and cytogram analysis on days 1, 3, and 7.
Main Results:
- The experimental group showed statistically significant reductions in IL-6, TNF-a, and CRP levels by day 7.
- Regenerative-inflammatory and regenerative cytogram types were significantly more prevalent in the experimental group on day 7.
- Probiotic antisepsis demonstrated a clear advantage in modulating the inflammatory response.
Conclusions:
- Probiotic antisepsis is an effective method for accelerating wound healing in type 2 diabetes patients.
- This approach offers a promising alternative for managing complex wound cases.
- Further research into probiotic applications in diabetic wound care is warranted.
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