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Updated: Jul 25, 2025

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Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
Published on: September 22, 2017
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NOVEL METHOD FOR VISUALIZING PERIPHERAL RETINAL STRUCTURES WITH MICROSCOPE-INTEGRATED OPTICAL COHERENCE TOMOGRAPHY
Frank L Brodie1, Henry Feng1, William Raynor1
1Departments of Ophthalmology, and.
Retinal Cases & Brief Reports
|June 26, 2023
Summary
Intraoperative optical coherence tomography (OCT) with a Goldmann lens enables visualization of peripheral retinal pathology. This method aids surgeons in identifying conditions like retinoschisis and retinal detachment.
Area of Science:
- Ophthalmology
- Medical Imaging
- Retinal Surgery
Background:
- Peripheral retinal imaging with optical coherence tomography (OCT) presents significant challenges.
- Accurate visualization of the peripheral retina is crucial for diagnosing and managing various ocular conditions.
Purpose of the Study:
- To describe a novel method for intraoperative OCT of the peripheral retina.
- To evaluate the utility of a microscope-integrated OCT system with a Goldmann lens for peripheral imaging.
Main Methods:
- Utilized an investigational microscope-integrated OCT system with real-time 4D volumetric imaging.
- Employed a Goldmann style mirrored contact lens intraoperatively in three patients.
- Captured peripheral retinal images during surgical procedures.
Main Results:
- Successfully visualized peripheral retinal structures, including retinoschisis.
- Identified a retinal break using the described peripheral OCT method.
- Detected areas of focal retinal detachment in the peripheral retina.
Conclusions:
- Intraoperative OCT combined with a Goldmann lens provides surgeons enhanced visualization of peripheral retinal pathology.
- This technique facilitates the evaluation of peripheral retinal conditions not easily assessed with conventional OCT.
- The described method offers a valuable tool for improving surgical outcomes in retinal procedures.
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