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Subretinal Transplantation of MACS Purified Photoreceptor Precursor Cells into the Adult Mouse Retina
Published on: February 22, 2014
ACUTE MACULAR NEURORETINOPATHY FOLLOWING SARS-CoV-2 VACCINATION
Miguel Gonçalves Afonso1, João Heitor Marques1, Sérgio Monteiro2
1Centro Hospitalar Universitário do Porto- Hospital de Santo António, Oporto, Portugal; and.
Purpose:
To report a case of acute macular neuroretinopathy (AMN) following SARS-CoV-2 vaccination.
Methods:
Case report.
Results:
An otherwise healthy 28-year-old white woman presented to an ophthalmology department with complaints of black paracentral vision scotomata on both eyes that appeared 2 days after receiving the first dose of Vaxzevria vaccine. Fundus examination revealed bilateral red brown petaloid lesions around the fovea. On spectral domain optical coherence tomography, a hyperreflective plaque between the outer plexiform and outer nuclear layers along with disruption of ellipsoid zone/interdigitation zone was observed. A diagnosis of AMN was made.
Conclusion:
AMN may be an extremely rare adverse event of SARS-COV-2 vaccination, especially in patients with other risk factors.
Synopsis:
An otherwise healthy 28-year-old white woman was diagnosed with AMN 2 days after SARS-CoV-2 vaccination.
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