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Updated: Jul 25, 2025
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
PIGMENTATION IN FOCAL SCLERAL NODULE
Christopher Go1,2,3, Adrian Mok1, Adrian T Fung1,2,3,4
1Department of Ophthalmology, Westmead Hospital, Westmead, NSW, Australia.
Purpose:
To report a case of pigmentation in focal scleral nodule (FSN).
Methods:
This is a single case report.
Result:
An asymptomatic 61-year-old woman was referred with small, partially pigmented raised lesion located at the superior margin of the optic nerve head. The lesion's clinical and multimodal imaging features were consistent for FSN including a dome-shaped elevation confined to the sclera with overlying choroidal thinning. However, the pigmentation within our lesion is a novel finding in FSN that has not been described before.
Conclusion:
To our knowledge, we report the first case of pigmentation in FSN. It is likely that our case was a typical FSN that then became pigmented, with melanosomes involving the flanges of the lesion where thin choroid remains. The understanding that FSN can be partially pigmented may eventually help unravel the origins of this poorly understood lesion.
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