Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fungal Group Zygomycota01:29

Fungal Group Zygomycota

58
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
58
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

43
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
43
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

3.9K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.9K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

12.0K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.0K
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

14
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
14
Fungal Phylum Basidiomycota01:26

Fungal Phylum Basidiomycota

137
Basidiomycota is a diverse phylum of fungi that includes ecologically significant decomposers such as white rot fungi, symbionts like mycorrhizal fungi, plant pathogens such as rusts and smuts, and edible species like Agaricus bisporus (the common button mushroom). These fungi play crucial roles in nutrient cycling, symbiotic relationships, and even human health. Their defining feature is the basidium, a microscopic club-shaped structure responsible for producing basidiospores.Fruiting Bodies...
137

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Managing Breakthrough Fungal Infections in Hematologic Patients: Determinants and Practical Management from a Latin American Perspective on Behalf of INFOCUS LATAM-ISHAM Working Group.

Microorganisms·2026
Same author

Repeat Blood Cultures in Persistent Febrile Neutropenia.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

A hospital-based retrospective study of hospitalizations with hyalohyphomycosis and phaeohyphomycosis in the United States.

Lancet regional health. Americas·2026
Same author

Redefining antifungal prophylaxis in acute leukaemia in the era of targeted therapies.

The Journal of antimicrobial chemotherapy·2026
Same author

Clinical Features and Mortality of Chronic Pulmonary Aspergillosis in Brazil: a Multicenter Cohort Study.

Open forum infectious diseases·2026
Same author

Immunoglobulin after bispecifics requires randomized trial.

Blood advances·2025

Related Experiment Video

Updated: Jul 25, 2025

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
07:42

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Published on: July 1, 2020

5.4K

Invasive Fungal Infections Associated with COVID-19.

Kyaw M Hlaing1, Lea M Monday1, Marcio Nucci2

  • 1Division of Infectious Diseases, Wayne State University School of Medicine, Detroit, MI 48201, USA.

Journal of Fungi (Basel, Switzerland)
|June 27, 2023
PubMed
Summary

Fungal infections like invasive aspergillosis complicated severe COVID-19, increasing mortality. Early diagnosis and antifungal therapy are crucial for better outcomes in critically ill patients.

Keywords:
COVID-19aspergillosiscandidiasismucormycosis

More Related Videos

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
04:37

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

Published on: February 2, 2024

875
Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
08:48

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis

Published on: March 19, 2019

7.0K

Related Experiment Videos

Last Updated: Jul 25, 2025

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
07:42

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Published on: July 1, 2020

5.4K
Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
04:37

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

Published on: February 2, 2024

875
Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
08:48

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis

Published on: March 19, 2019

7.0K

Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Mycology

Background:

  • The COVID-19 pandemic resulted in millions of deaths, frequently due to respiratory failure.
  • Hospitalized patients, especially in intensive care units (ICUs), experienced severe complications.
  • Fungal infections, including invasive aspergillosis, candidiasis, and mucormycosis, significantly contributed to morbidity and mortality.

Purpose of the Study:

  • To highlight the significant burden of fungal infections in COVID-19 patients.
  • To discuss the risk factors and diagnostic challenges associated with these infections.
  • To emphasize the need for early diagnosis and treatment to improve patient outcomes.

Main Methods:

  • Review of clinical data and literature concerning fungal infections in COVID-19 patients.
  • Analysis of risk factors, including viral-induced immune alterations and therapeutic immunosuppression.
  • Evaluation of diagnostic limitations and their impact on patient management.

Main Results:

  • COVID-19 patients, particularly those in ICUs, are at high risk for invasive fungal infections.
  • Risk factors include COVID-19's impact on immune defenses and immunosuppressive therapies.
  • Current diagnostic tests often lack sensitivity, leading to delayed diagnosis.
  • Mortality rates for these fungal infections can exceed 50% in some patient cohorts.

Conclusions:

  • Invasive fungal infections pose a serious threat to critically ill COVID-19 patients.
  • A high index of clinical suspicion is essential for prompt diagnosis.
  • Early initiation of appropriate antifungal therapy is critical for improving survival rates.