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Updated: Jul 25, 2025

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Analysis of Fatty Acid Content and Composition in Microalgae
Published on: October 1, 2013
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Extraction of Nannochloropsis Fatty Acids Using Different Green Technologies: The Current Path
Sérgio Cruz Sousa1,2, Ana Cristina Freitas1, Ana Maria Gomes1
1CBQF-Centro de Biotecnologia e Química Fina, Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.
Marine Drugs
|June 27, 2023
Summary
This review explores green technologies for extracting valuable lipids, like polyunsaturated fatty acids (PUFA), from Nannochloropsis microalgae. Combining methods enhances extraction efficiency for specific fatty acids, including eicosapentaenoic acid.
Area of Science:
- Biotechnology
- Marine Biology
- Sustainable Chemistry
Background:
- Nannochloropsis microalgae are rich sources of polyunsaturated fatty acids (PUFA).
- Traditional lipid extraction uses hazardous organic solvents.
- Greener alternatives are needed to improve sustainability.
Purpose of the Study:
- To review recent (last 5 years) technologies for extracting fatty acids from Nannochloropsis.
- To assess methods for increasing extraction yields of valuable lipids.
- To identify optimal technologies for specific fatty acid recovery.
Main Methods:
- Review of extraction technologies including cell disruption and direct extraction.
- Analysis of independent and combined technology applications.
- Evaluation of extraction efficacy across different Nannochloropsis species.
Main Results:
- Various green technologies enhance fatty acid extraction from Nannochloropsis.
- Combined technologies often prove more effective than individual methods.
- Extraction efficiency and lipid profiles depend on the technology and Nannochloropsis species.
Conclusions:
- Tailored technology selection is crucial for efficient PUFA recovery, including eicosapentaenoic acid.
- A case-by-case assessment is necessary to optimize extraction for specific fatty acids.
- Advancements in green extraction technologies offer sustainable routes to valuable microalgal lipids.
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