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[Basic nephropathology for pathologists-part 2 : Non-inflammatory lesions].
Ariana Gaspert1, Maike Büttner-Herold2, Kerstin Amann2
1Abteilung für Nephropathologie, Institut für Pathologie und Molekularpathologie, Universitätsspital Zürich, Schmelzbergstr. 12, 8091, Zürich, Schweiz. ariana.gaspert@usz.ch.
Pathologie (Heidelberg, Germany)
|June 27, 2023
Summary
Non-cancerous kidney lesions found during tumor removal can significantly impact patient prognosis. This review covers common noninflammatory changes in kidney biopsies for pathologists.
Area of Science:
- Nephropathology
- Renal Pathology
- Oncologic Pathology
Context:
- Kidney biopsy evaluation for renal diseases and transplants is typically centralized.
- Nonneoplastic renal lesions in nephrectomies for tumors can have significant prognostic value.
- These findings are crucial for patients with localized tumors and good tumor-specific survival.
Purpose:
- To discuss common noninflammatory lesions in the vascular, glomerular, and tubulo-interstitial compartments of the kidney.
- To provide basic nephropathology insights for pathologists.
- To highlight the prognostic importance of non-tumor-related kidney pathology.
Summary:
- This content focuses on noninflammatory lesions in nonneoplastic kidney tissue, often found incidentally during nephrectomies for renal tumors.
- Key areas covered include vascular, glomerular, and tubulo-interstitial changes, such as ischemic, vascular alterations, and diabetic nephropathy.
- The prognostic significance of these findings can outweigh that of the tumor itself in certain patient cohorts.
Impact:
- Enhances diagnostic capabilities for pathologists interpreting kidney biopsies.
- Improves prognostic assessment in patients undergoing nephrectomy for renal tumors.
- Contributes to a better understanding of nonneoplastic renal diseases in the context of oncologic surgery.
Keywords:
Diabetic nephropathyDifferential diagnosisHypertensionNephropathyThrombotic microangiopathyMore Related Videos
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