Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Man-in-the-barrel syndrome.

J I Sage, R L Van Uitert

    Neurology
    |August 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    The "man-in-the-barrel" syndrome (MIB) is a serious condition following systemic hypotension. Patients with MIB have a significantly poorer prognosis for survival and recovery compared to those without the syndrome.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The tau A0 allele in Parkinson's disease.

    Movement disorders : official journal of the Movement Disorder Society·2001
    Same author

    Depression and anxiety in Parkinson's disease: possible effect of genetic variation in the serotonin transporter.

    Journal of geriatric psychiatry and neurology·1999
    Same author

    Pharmacoeconomic analysis of using Sinemet CR over standard Sinemet in parkinsonian patients with motor fluctuations.

    The Annals of pharmacotherapy·1998
    Same author

    Association of long variants of the dopamine D4 receptor exon 3 repeat polymorphism with Parkinson's disease.

    Clinical genetics·1998
    Same author

    Association of a serotonin transporter gene promoter polymorphism with harm avoidance behaviour in an elderly population.

    Psychiatric genetics·1998
    Same author

    Ten years' experience with enteral levodopa infusions for motor fluctuations in Parkinson's disease.

    Movement disorders : official journal of the Movement Disorder Society·1998
    Same journal

    Factors Associated With Disability Improvement and Worsening Independent of Attacks in Patients With AQP4-IgG+ NMOSD and MOGAD: A Multicenter Cohort Study.

    Neurology·2026
    Same journal

    Cost-Effectiveness of Intracranial Aneurysm Screening: A Systematic Review.

    Neurology·2026
    Same journal

    Rare Eating Epilepsy: Co-Occurrence of Focal Cortical Dysplasia and Gray Matter Heterotopia.

    Neurology·2026
    Same journal

    Spatiotemporal Associations Between Cortical Microinfarcts and Cortical Superficial Siderosis in Cerebral Amyloid Angiopathy.

    Neurology·2026
    Same journal

    Blood-Brain Barrier Disruption Before Interhospital Transfer for Thrombectomy and Clinical Outcome.

    Neurology·2026
    Same journal

    At Death's Door: Cytosolic Dopamine in Patients With Parkinson Disease.

    Neurology·2026
    See all related articles

    Area of Science:

    • Neurology
    • Critical Care Medicine
    • Neuroscience

    Background:

    • Systemic hypotension can lead to severe neurological complications.
    • The "man-in-the-barrel" syndrome (MIB) is a recognized neurological deficit following such events.
    • Understanding the prognosis associated with MIB is crucial for patient management.

    Purpose of the Study:

    • To investigate the incidence and prognosis of the "man-in-the-barrel" syndrome (MIB) in comatose patients after systemic hypotension.
    • To compare survival and recovery rates between patients with and without MIB.

    Main Methods:

    • A prospective study was conducted on 34 comatose patients experiencing systemic hypotension.
    • Patients were assessed for the presence of MIB, characterized by preserved leg movement but absent arm movement.

    Related Experiment Videos

  • Survival and recovery outcomes were recorded and compared between MIB and non-MIB groups.
  • Main Results:

    • Eleven of 34 patients (32%) developed MIB.
    • Survival to hospital discharge was significantly lower in patients with MIB (9%) compared to those without MIB (35%).
    • Even among patients with preserved reflexes and limb movement at 24 hours, MIB was associated with a poorer survival rate (11% vs. 67%).

    Conclusions:

    • The "man-in-the-barrel" syndrome is a common complication of cerebral hypoperfusion.
    • MIB is associated with a poor prognosis and significantly reduced survival rates.
    • Early neurological assessments, including reflex and limb movement evaluation, are important for predicting outcomes in these patients.