Experimental studies with a high-density silicone oil for giant retinal tear

Fluorsilicone oil of high density (1.3 g/cm3) injected into the vitreous cavity after vitrectomy filled the rabbit eyeball in an anterior-posterior direction and unfolded a giant retinal tear (produced by peripheral retinotomy). Fluorsilicone oil injected into the anterior chamber causes a localized opacification of the cornea. Histologically, a fibroplastic metaplasia of the deep corneal layers with a newly formed posterior collagenous layer was found. Histologic findings were identical in fellow eyes in which polydimethylsilicone was used as a control substance.