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Published on: December 6, 2016
A Prospective Study on Obstructive Sleep Apnea, Clinical Profile and Polysomnographic Variables
Geetha Kandasamy1, Tahani Almeleebia1
1Department of Clinical Pharmacy, College of Pharmacy, King Khalid University (KKU), Abha 61421, Saudi Arabia.
Obstructive sleep apnea (OSA) is common, especially in men, and linked to obesity. Polysomnography effectively detects nocturnal desaturations in OSA patients, enabling early treatment.
Area of Science:
- Sleep Medicine
- Pulmonology
- Cardiorespiratory Health
Background:
- Obstructive sleep apnea (OSA) involves pharyngeal collapse during sleep, leading to cardiorespiratory and neurological imbalances.
- High prevalence of obesity and OSA observed, particularly in men.
Purpose of the Study:
- To assess obstructive sleep apnea (OSA) prevalence.
- To investigate the relationship between the apnea-hypopnea index (AHI) and polysomnographic characteristics in OSA patients.
Main Methods:
- Prospective study over two years involving 216 participants.
- Polysomnography used for diagnosis; 175 patients diagnosed with OSA (AHI ≥ 5).
- Statistical analysis included ANOVA and Pearson's correlation coefficient.
Main Results:
- Average AHI varied by severity: mild (11.79 ± 3.55), moderate (22.12 ± 4.34), severe (59.16 ± 22.15 events/hour).
- Significant correlations found between AHI and BMI, oxygen saturation, oxygen desaturation events, snoring duration, and number of snores.
- Obesity (BMI) and nocturnal desaturations are key findings in OSA patients.
Conclusions:
- Obstructive sleep apnea (OSA) is prevalent, often associated with obesity, particularly in males.
- Nocturnal desaturations are a common characteristic of OSA.
- Polysomnography is crucial for early detection and management of this treatable condition.
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