Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vertical and Horizontal Ridge Augmentation with Titanium-Reinforced Dense PTFE and Reinforced PTFE Mesh: A Prospective Comparative Case Series.

Journal of functional biomaterials·2026
Same author

Distinct Osteogenic Profiles of Tetracyclines from Different Generations in an Ex Vivo Embryonic Chick Femur Model.

International journal of molecular sciences·2026
Same author

Calcium ionic replacement in sodium trimetaphosphate particles: a novel strategy for bone tissue engineering.

Journal of materials science. Materials in medicine·2026
Same author

Correlation of Antioxidant and Antibacterial Activities of the Aqueous <i>Pinus pinaster</i> Aiton Bark Extract Within a Cytocompatible Concentration Range.

Antioxidants (Basel, Switzerland)·2025
Same author

Antifungal Activity, Cytocompatibility, and Wound Healing Potential of Novel Mucoadhesive Formulations for Oral Drug Delivery.

Journal of biomedical materials research. Part A·2025
Same author

Response of cultured primary gingival and periodontal ligament cells to angiotensin II and IL1β challenges.

Brazilian oral research·2025

Related Experiment Video

Updated: Jul 25, 2025

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering
09:49

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering

Published on: February 23, 2024

1.8K

Bioengineering Composite Aerogel-Based Scaffolds That Influence Porous Microstructure, Mechanical Properties and In

Mariana Souto-Lopes1,2,3, Maria Helena Fernandes4,5, Fernando Jorge Monteiro1,2,3,6

  • 1i3S-Instituto de Investigação e Inovação em Saúde da Universidade do Porto, 4200-135 Porto, Portugal.

Materials (Basel, Switzerland)
|June 28, 2023
PubMed
Summary

Bone tissue engineering uses advanced aerogel scaffolds to repair large bone defects. These biomimetic materials show promise for bone regeneration, but further development is needed for clinical application.

Keywords:
aerogelsbiomaterialsbone regenerationcomposite scaffoldsmechanical propertiesporous microstructure

More Related Videos

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
07:14

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Published on: July 27, 2022

3.7K
Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

9.8K

Related Experiment Videos

Last Updated: Jul 25, 2025

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering
09:49

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering

Published on: February 23, 2024

1.8K
Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
07:14

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Published on: July 27, 2022

3.7K
Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

9.8K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Orthopedic Engineering

Background:

  • Large bone defects pose significant clinical challenges for regeneration.
  • Bone tissue engineering utilizes biomimetic scaffolds to mimic the native bone extracellular matrix.
  • Aerogel scaffolds offer a promising platform for bone regeneration due to their tunable properties.

Purpose of the Study:

  • To review recent advancements in aerogel composite scaffolds for bone tissue engineering.
  • To discuss cutting-edge technologies and biomaterials used in aerogel scaffold fabrication.
  • To identify current challenges and future directions in aerogel scaffold development for bone regeneration.

Main Methods:

  • Review of recently published studies on organic/inorganic aerogel composite scaffolds.
  • Analysis of scaffold properties, including microstructure, porosity, and mechanical strength.
  • Evaluation of in vivo studies assessing bone regeneration potential.

Main Results:

  • Aerogel scaffold preparation methods have improved, balancing porosity and mechanical resistance.
  • In vivo studies demonstrate the potential of aerogel scaffolds in critical bone defect repair.
  • Challenges remain in optimizing scaffold properties and mimicking native bone complexity.

Conclusions:

  • Aerogel composite scaffolds represent a significant advancement in bone tissue engineering.
  • Further research is needed to enhance scaffold performance and address current limitations.
  • Development of advanced 3D in vitro models is crucial to reduce reliance on animal studies.