Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Single-Strand DNA Binding Proteins01:03

Single-Strand DNA Binding Proteins

14.4K
For successful DNA replication, the unwinding of double-stranded DNA must be accompanied by stabilization and protection of the separated single strands of the DNA. This crucial task is performed by single-strand DNA-binding (SSB) proteins. They bind to the DNA in a sequence-independent manner, which means that the nitrogenous bases of the DNA need not be present in a specific order for binding of SSB proteins to it. The binding of SSB proteins straightens single-stranded DNA (ssDNA) and makes...
14.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spin-driven enantioselective regulation of cyclooxygenase-2 activity for rheumatoid arthritis therapy via chiral gold nanohelices.

Nature communications·2026
Same author

Topologically Nontrivial Phase and Phase Transition in Helicenes Induced by Gate Electric Field and Mechanical Strain.

The journal of physical chemistry letters·2026
Same author

Deskarene: Single-Molecule Conductance and Mixed-Valence Character of Diferrocene-Based Ladder-Type Conjugated Molecules.

Organic letters·2026
Same author

Anomalous Magnetoresistance beyond the Jullière Model for Spin Selectivity in Chiral Molecules.

The journal of physical chemistry letters·2025
Same author

Spin-to-Charge Conversion Modulated by Chiral Molecules.

The journal of physical chemistry letters·2025
Same author

Enhanced electron transport and self-similarity in quasiperiodic borophene nanoribbons with line defects.

Nanoscale·2023

Related Experiment Video

Updated: Jul 25, 2025

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
05:37

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

765

Spin-selectivity effect of G-quadruplex DNA molecules.

Lei Deng1, Irfan Hussain Bhat1, Ai-Min Guo1

  • 1Hunan Key Laboratory for Super-microstructure and Ultrafast Process, School of Physics and Electronics, Central South University, Changsha 410083, China.

The Journal of Chemical Physics
|June 28, 2023
PubMed
Summary

Chirality-induced spin selectivity in guanine-quadruplex (G4) DNA is dominated by external factors, not inherent molecular chirality. This effect is robust and offers new ways to enhance spin selectivity in chiral nanodevices.

More Related Videos

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
08:28

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers

Published on: September 19, 2017

8.0K
Author Spotlight: Characterizing DNA G-Quadruplex by Bis-3-Chloropiperidine Based Chemical Mapping
05:32

Author Spotlight: Characterizing DNA G-Quadruplex by Bis-3-Chloropiperidine Based Chemical Mapping

Published on: May 12, 2023

1.4K

Related Experiment Videos

Last Updated: Jul 25, 2025

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
05:37

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

765
Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
08:28

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers

Published on: September 19, 2017

8.0K
Author Spotlight: Characterizing DNA G-Quadruplex by Bis-3-Chloropiperidine Based Chemical Mapping
05:32

Author Spotlight: Characterizing DNA G-Quadruplex by Bis-3-Chloropiperidine Based Chemical Mapping

Published on: May 12, 2023

1.4K

Area of Science:

  • Molecular electronics
  • Spintronics
  • DNA nanotechnology

Background:

  • Chirality-induced spin selectivity (CISS) is a phenomenon observed in chiral molecules.
  • CISS typically arises from inherent molecular chirality.
  • Guanine-quadruplex (G4) DNA is a promising candidate for molecular electronics.

Purpose of the Study:

  • To theoretically investigate spin-dependent electron transport in G4 DNA molecular junctions.
  • To determine the dominant source of spin selectivity in G4 DNA.
  • To explore the robustness and potential applications of CISS in G4 DNA.

Main Methods:

  • Development of a theoretical model for spin-dependent electron transport.
  • Inclusion of molecule-electrode contact and weak spin-orbit coupling.
  • Simulation of electron transport through G4 DNA connected to nonmagnetic electrodes.

Main Results:

  • G4 DNA molecular junctions exhibit significant spin-selectivity.
  • Asymmetric contact-induced external chirality, not inherent molecular chirality, dictates spin filtration efficiency.
  • The spin-selectivity effect is robust against disorder and parameter variations.

Conclusions:

  • External chirality at molecule-electrode contacts is crucial for spin selectivity in G4 DNA.
  • G4 DNA offers a viable platform for achieving spin selectivity.
  • These findings provide a pathway for improving spin selectivity in chiral nanodevices through contact engineering.