Physical Activity Interventions for Improving Cognitive Functions in Children With Autism Spectrum Disorder: Protocol...

Area of Science:

• Neuroscience
• Developmental Psychology
• Pediatrics

Background:

• Autism spectrum disorder (ASD) affects millions of children globally, with early intervention significantly impacting outcomes.
• Physical activity interventions show promise for children with ASD, but their comparative efficacy is unclear.

Purpose of the Study:

• To update the literature on physical activity interventions for children with ASD.
• To explore the efficacy of various physical activity intervention strategies on cognitive functions in children with ASD.

Main Methods:

• A systematic review and network meta-analysis (NMA) following PRISMA-NMA guidelines.
• Searched 9 databases for studies on children (0-12 years) with ASD and physical activity interventions measuring cognitive outcomes.
• Evaluated study quality using the Grading of Recommendations Assessment, Development, and Evaluation framework and analyzed data using RStudio and Comprehensive Meta-Analysis software.

Main Results:

• Preliminary search identified 3778 studies; final eligible studies are anticipated to be between 30 and 50.
• Ongoing screening based on inclusion/exclusion criteria.

Conclusions:

• This study will provide a comprehensive review and NMA of physical activity interventions for children with ASD.
• Findings will inform clinical practice and future research, supporting physical activity as a key early intervention component for ASD.