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Gesche Jürgens1, Poul Jørgen Jennum2,3, Lone Baandrup3,4

  • 1Klinisk Farmakologisk Enhed, Sjællands Universitetshospital, Roskilde.

Ugeskrift for Laeger
|June 29, 2023
PubMed
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Common medications can disrupt sleep patterns and architecture by affecting neurotransmitter systems or causing side effects. Clinicians must assess medication

Area of Science:

  • Pharmacology
  • Sleep Medicine
  • Neuroscience

Background:

  • Assessing medication status is crucial for patients with disturbed sleep complaints.
  • Medications can impact sleep continuity and architecture through direct neurotransmitter effects or indirect side effects.

Approach:

  • This review summarizes the effects of common medications on sleep patterns.
  • It highlights the importance of evaluating medication's role in sleep disturbances.

Key Points:

  • Medications influence sleep directly via neurotransmitter systems (e.g., serotonin, dopamine) and indirectly through therapeutic benefits or adverse effects.
  • Polypharmacy increases the risk of significant sleep disruption.
  • Clinicians need to be aware of medication-induced sleep disturbances.

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Conclusions:

  • Adjusting medication regimens is essential to prevent disrupted sleep patterns and subsequent daytime impairment.
  • Understanding medication's impact on sleep is vital for effective patient management and improving quality of life.