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Updated: Jul 25, 2025

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
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US Cancer Mortality Trends Among Hispanic Populations From 1999 to 2020.

Isabella R Pompa1, Anushka Ghosh1, Shamik Bhat2

  • 1Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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Cancer mortality decreased overall for Hispanic individuals, but liver cancer deaths rose for men and women, and pancreas and uterine cancer deaths increased for women. Targeted interventions are needed to address these specific cancer trends.

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Area of Science:

  • Oncology
  • Public Health
  • Epidemiology

Background:

  • Cancer is the leading cause of death for Hispanic individuals in the US, despite overall decreases in cancer mortality.
  • Understanding trends in cancer-specific mortality (CSM) among Hispanic populations is crucial for developing targeted public health strategies.

Purpose of the Study:

  • To analyze longitudinal cancer mortality trends from 1999 to 2020 among Hispanic individuals.
  • To compare age-adjusted cancer death rates between Hispanic and other racial/ethnic populations.

Main Methods:

  • A cross-sectional study using the CDC WONDER database to extract age-adjusted cancer death rates from 1999-2020.
  • Analysis included demographic characteristics, cancer types, and US census regions.
  • Cancer death rates for other racial and ethnic populations were extracted for comparison in 2000, 2010, and 2020.

Main Results:

  • Overall CSM rates among Hispanic individuals decreased by 1.3% annually, with greater decreases in men than women.
  • However, mortality rates for liver cancer increased among Hispanic men and women, and for pancreas and uterine cancers among Hispanic women.
  • Significant increases in liver cancer mortality were observed in the Western US for both Hispanic men and women.

Conclusions:

  • Despite an overall decline, specific cancer types show increasing mortality among Hispanic populations.
  • Disparities in CSM rates exist across age groups and US regions.
  • Sustainable, targeted interventions are necessary to reverse adverse cancer mortality trends in Hispanic communities.