Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cell ultrastructure in disease.

R Laschi, E Govoni

    Scanning Electron Microscopy
    |January 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Modern medicine requires a cellular perspective for disease evaluation. Understanding ultrastructural changes in cell organelles is key for accurate diagnosis and targeted molecular therapies.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    An animal model based on the Sprague Dawley rat for the evaluation of ototoxicity.

    Annals of the New York Academy of Sciences·2000
    Same author

    Intra-articular hyaluronic acid in the treatment of osteoarthritis of the knee: clinical and morphological study.

    Clinical and experimental rheumatology·1998
    Same author

    Aging of the human synovium: an in vivo and ex vivo morphological study.

    Seminars in arthritis and rheumatism·1992
    Same author

    Comparative ototoxic potential of hyaluronic acid and methylcellulose.

    Acta oto-laryngologica·1992
    Same author

    [Spontaneous reparation of post-traumatic tympanic perforation: an experimental study in rats].

    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale·1990
    Same author

    Healing of prosthetic arterial grafts.

    Scanning microscopy·1990
    Same journal

    Statoconia formation in molluscan statocysts.

    Scanning electron microscopy·1986
    Same journal

    Statolith formation in Cnidaria: effects of cadmium on Aurelia statoliths.

    Scanning electron microscopy·1986
    Same journal

    Phase transitions of calcium oxalate trihydrate and epitaxy in the weddellite-whewellite system.

    Scanning electron microscopy·1986
    Same journal

    Experimental investigation of the genesis of struvite stones in cats.

    Scanning electron microscopy·1986
    Same journal

    Analysis of canine urinary stones using infrared spectroscopy and scanning electron microscopy.

    Scanning electron microscopy·1986
    Same journal

    Otoconia as test masses in biological accelerometers: what can we learn about their formation from evolutionary studies and from work in microgravity?

    Scanning electron microscopy·1986
    See all related articles

    Area of Science:

    • Cellular biology
    • Pathology
    • Medical diagnostics

    Background:

    • Clinical signs and symptoms often originate from diseased cell organelles.
    • Effective therapeutic interventions require targeting specific sites of cellular lesions.

    Purpose of the Study:

    • To propose a paradigm shift in clinical thinking, emphasizing the correlation between symptoms and submicroscopic cellular alterations.
    • To highlight the practical utility of an ultrastructural approach in medicine.

    Main Methods:

    • Review of clinical experience and scientific literature.
    • Emphasis on the application of electron microscopy for identifying subcellular modifications.

    Main Results:

    • Electron microscopy allows for fine differential diagnosis by revealing structural subcellular changes.

    Related Experiment Videos

  • This approach facilitates a deeper understanding of disease pathogenesis.
  • It aids in establishing guidelines for precise molecular-level pharmacological interventions.

    • Conclusions:

    • Adopting a 'cellular way of thinking' is essential for contemporary medical practice.
    • Targeting diseased organelles offers a precise therapeutic strategy.
    • Ultrastructural analysis via electron microscopy is crucial for advanced diagnostics and treatment planning.