Related Experiment Video

Updated: Jul 25, 2025

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD
10:02

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Published on: March 12, 2020

15.8K

Rapid response events with multiple triggers are associated with poor outcomes in children

Erin M Kritz1,2, Jenilea K Thomas1,2, Nawara S Alawa1,2

  • 1Department of Pediatric Critical Care, Baylor College of Medicine, Houston, TX, United States.

Frontiers in Pediatrics
|June 30, 2023
PubMed

Insights

Pediatric rapid response team (RRT) events with multiple triggers are linked to worse outcomes, including cardiopulmonary arrest and longer ICU stays. Understanding these associations aids clinical decisions and resource allocation.

Area of Science:

  • Pediatric critical care medicine
  • Healthcare quality improvement
  • Clinical event analysis

Background:

  • Pediatric rapid response teams (RRTs) are crucial for early intervention in deteriorating patients.
  • Understanding the factors influencing RRT event outcomes is essential for optimizing patient care.
  • Previous studies have explored RRT triggers, but the impact of multiple triggers on outcomes requires further investigation.

Purpose of the Study:

  • To characterize pediatric RRT events and their outcomes.
  • To determine the association between RRT trigger types and patient outcomes.
  • To test the hypothesis that multiple RRT triggers are associated with adverse outcomes.

Main Methods:

  • Retrospective analysis of 2,267 RRT events over three years at a tertiary academic pediatric hospital.
  • Inclusion of all patients with index RRT events during the study period.
  • Statistical analysis of patient demographics, RRT trigger reasons, and clinical outcomes such as ICU transfer, need for advanced cardiopulmonary support, length of stay, and mortality.

Main Results:

  • The majority of RRT events were triggered by respiratory issues (36%) or multiple factors (35%).
  • Multiple RRT triggers were significantly associated with increased likelihood of ICU transfer (OR 1.48), need for advanced cardiopulmonary support (OR 1.68), cardiopulmonary arrest (OR 2.36), and longer ICU length of stay.
  • Patients with multiple RRT triggers experienced higher rates of cardiopulmonary arrest and required more advanced support compared to single-trigger events.

Conclusions:

  • Pediatric RRT events involving multiple triggers are associated with significantly worse clinical outcomes.
  • These findings highlight the importance of recognizing complex RRT events for timely and appropriate interventions.
  • Knowledge of trigger-outcome associations can inform clinical decision-making, care planning, and resource allocation in pediatric critical care settings.
Abstract

Keywords:
cardiopulmonary arrest (cpa)critical deteriorationpediatric ICUpediatric outcomesrapid responsetriggers

More Related Videos

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy08:26

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy

Published on: January 11, 2016

12.2K
An Electrophysiology Protocol to Measure Reward Anticipation and Processing in Children05:04

An Electrophysiology Protocol to Measure Reward Anticipation and Processing in Children

Published on: October 4, 2018

7.0K

Related Concept Videos

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
133
Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.0K
Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
76
Conduct Disorder01:28

Conduct Disorder

Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...
91