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Sandpaper: Efficient Medium for Analysis of Polishable Solid Samples by Ambient Mass Spectrometry.

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A new method, sandpaper spray mass spectrometry (SPS-MS), uses sandpaper to analyze solid samples like coffee beans. This technique efficiently identifies compounds and offers advantages over existing methods for hard surfaces.

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Area of Science:

  • Analytical Chemistry
  • Material Science

Background:

  • Paper spray mass spectrometry (PS-MS) is a common technique for analyzing various samples.
  • Analyzing hard solid samples with PS-MS can be challenging due to sample preparation difficulties.

Purpose of the Study:

  • To introduce a novel mass spectrometry technique for analyzing polishable solid samples.
  • To demonstrate the efficacy of sandpaper as a substrate for spray mass spectrometry.

Main Methods:

  • Developed sandpaper spray mass spectrometry (SPS-MS) using sandpaper as the sample medium.
  • Analyzed coffee beans (n=100) by sanding their surfaces and applying methanol and high voltage.
  • Utilized positive and negative ion modes for mass spectrometry analysis.

Main Results:

  • Successfully identified numerous compounds in coffee beans, including caffeine, sugars, and carboxylic acids.
  • SPS-MS proved effective for analyzing polishable solid samples, showing advantages over PS-MS.
  • The technique simplifies the analysis of hard samples compared to cutting tissue pieces.

Conclusions:

  • SPS-MS is a straightforward and efficient method for analyzing polishable solid samples.
  • The technique is versatile and has potential applications for analyzing wood, plastic, and crop grains.
  • SPS-MS offers a practical alternative for mass spectrometry analysis of challenging sample types.