[Properties of liposomes adsorbed by montmorillonite]

Adsorption of phosphatidylcholine liposomes by montmorillonite was studied for its effect on peroxidation of phospholipids and structure of the bilayer. The UV spectroscopy has shown that adsorption decreases peroxidation of lipids. A parameter is suggested for estimating an oxidation degree of lipids at the stage of the intensive formation of secondary products of their peroxidation. Fluorescent probes (1-anilinonaphthalene-8-sulphonate and pyrene) are used to establish that structural changes of the bilayer take place in adsorbed liposomes being followed by a decrease in the mobility of surface zones of phospholipid "heads" and by an increase in the polarity of hydrophobic parts of the bilayer.