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Undifferentiated Pleomorphic Sarcoma Invading the Internal Jugular Vein.
1Gunma University Heavy Ion Medical Center, Gunma, Japan; Department of Oral and Maxillofacial Surgery/Plastic Surgery, Gunma University Graduate School of Medicine, Gunma, Japan.
Practical Radiation Oncology
|June 30, 2023
Summary
This study reports a rare case of vascular invasion in undifferentiated pleomorphic sarcoma (UPS) recurrence. Post-surgery changes may have facilitated tumor invasion into the internal jugular vein.
Area of Science:
- Oncology
- Radiotherapy
- Surgical Pathology
Background:
- Undifferentiated pleomorphic sarcoma (UPS) is a rare soft tissue sarcoma.
- Carbon ion radiotherapy (C-ion RT) is an advanced treatment modality.
- Pterygopalatine fossa and parotid gland are critical anatomical locations.
Observation:
- A 60-year-old woman with UPS in the left pterygopalatine fossa received C-ion RT.
- Post-treatment, metastasis to the left parotid gland was treated with surgery.
- Follow-up MRI revealed invasion of the left internal jugular vein.
Findings:
- Pathology confirmed parotid lymph node metastasis but no initial vascular invasion.
- Vascular invasion into the internal jugular vein was suspected post-surgery.
- This represents a potentially novel presentation of UPS recurrence.
Implications:
- This case highlights a rare instance of vascular invasion in UPS, a pattern not previously documented.
- Perivascular tissue changes post-neck dissection may contribute to tumor vascular invasion.
- Further research is needed to understand and manage this rare complication.
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