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Related Concept Videos

Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

36
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

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Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Tissue Transplantation01:24

Tissue Transplantation

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

201
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
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Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Related Experiment Video

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Small Bowel Transplantation In Mice
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Pediatric Intestinal Transplantation Management and Outcomes.

Kera McNelis1,2, Michael E Rogers1,2, Samuel Kocoshis1,2

  • 1Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

Neoreviews
|June 30, 2023
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Intestinal failure, a loss of nutrient absorption, often requires parenteral nutrition in children. Intestinal transplantation is a life-saving option for severe cases, despite lifelong immunosuppression needs and potential complications.

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Area of Science:

  • Pediatric Gastroenterology
  • Transplant Surgery
  • Immunology

Background:

  • Intestinal failure significantly impairs nutrient absorption, necessitating supportive therapies.
  • Parenteral nutrition is the primary treatment for pediatric intestinal failure.
  • Intestinal transplantation is a critical intervention for life-threatening complications.

Purpose of the Study:

  • To review the role and outcomes of intestinal transplantation in children with intestinal failure.
  • To highlight the multidisciplinary approach required for pre- and post-transplant care.
  • To discuss the challenges and advancements in pediatric intestinal transplantation.

Main Methods:

  • Review of current literature and clinical practices in pediatric intestinal transplantation.
  • Analysis of outcomes, complications, and management strategies.
  • Emphasis on the evaluation and rehabilitation process for potential transplant candidates.

Main Results:

  • Intestinal transplantation has shown improved outcomes in recent years.
  • Key complications include acute cellular rejection, graft-versus-host disease, infection, and PTLD.
  • Lifelong immunosuppression and intensive medical management are required post-transplant.

Conclusions:

  • Intestinal transplantation is a viable, life-saving option for select children with intestinal failure.
  • Multidisciplinary care and extensive evaluation are crucial for successful transplantation.
  • Ongoing research and management strategies continue to improve long-term outcomes.